A blood test for a coagulogram is an analysis showing blood clotting. It is necessary in pregnancy, preparing the patient for surgery. That is, in such cases, when a person is expected to lose blood. In such situations, this type of blood test is necessary! The analysis of a blood on a coagulogram and what it is, let's understand more in detail. This type of analysis is also carried out in a comprehensive study of varicose veins, liver disease and immunodeficiency.
Blood clotting is the defense of the body against bleeding. With a cut or some other tissue damage, the blood cells activate and form a stopper to stop the blood. These cells are called platelets. In a normal state, platelets should not manifest themselves in any way, because in order to move along the blood vessels, the blood must be liquid and fluid. A blood test for a coagulogram at a normal rate will show the blood's ability to remain liquid and at the same time curl up when damaged.
Increased coagulability leads to such dangerous co
Coagulogram in pregnancy
Even more important is to make the correct interpretation of the blood test for pregnancy. An interesting fact is that this analysis will show increased blood coagulation, this is the norm in pregnancy. However, this is not an excuse not to follow this indicator and to refuse analysis. Changes in the structure of blood coagulability can affect the entire pregnancy, as well as the brain of the child, if not in time to identify these violations. Therefore, a woman needs to know what indicators in itself contain this analysis and how it surrenders.
This kind of analysis is given on an empty stomach, you can not eat anything for 8 hours before the analysis. Blood is taken from the vein. The interpretation of the blood test for a coagulogram during pregnancy consists of the following indices.
1) Fibrinogen is a special protein. It rises throughout the entire pregnancy, up to delivery itself and the maximum should be 6 g / l.
2) APTT( activated partial thromboplastin time).This indicator for pregnancy, in contrast to fibrinogen, should be reduced. Normally, when analyzing blood for a coagulogram, this indicator is 17-20 seconds.
3) Lupus anticoagulant is intended to show antibodies that make APTTV grow. Therefore, during pregnancy, it should not be. If a lupus anticoagulant is detected in the analysis, then this indicates an autoimmune disease.
These are the main indicators for pregnancy. Let's see what indicators should be in a normal state in humans.
Decoding the blood test for the coagulogram
To list the main normal units, we need to list all the indicators involved in the study.
Prothrombin is a protein of blood clotting. In the analysis, its content in the blood is determined. The time that the stopping of blood after a puncture is the most important indicator for evaluating the work of platelets. A healthy person should stop the blood for 2-3 minutes. If it took more time, then what does it mean? This factor may indicate a lack of vitamin C. Also, an increase in bleeding stopping time can be observed with the use of drugs that dilute blood( aspirin).Prothrombin is synthesized in the liver with the participation of vitamin K. When deciphering the analysis, prothrombin will help to identify the presence of diseases of the gastrointestinal tract.
Fibrinogen is an indicator that influences the determination of clotting time. It should be 11-17.8 seconds. This is considered the norm. This protein is synthesized, like prothrombin in the liver. Under what circumstances is an increase in fibrinogen? This pregnancy( last trimester), after childbirth, pneumonia, myocardial infarction, stroke, decreased thyroid function, burns. Reduction of fibrinogen can indicate cirrhosis, lack of vitamin C or B12, toxicosis during pregnancy.
Antithrombin is a protein that helps to resolve the thrombus afterwards.
Adhesion - the ability of platelets to form a thrombus to close the damaged site, that is, stick to the walls of the vessels. A decrease in this indicator indicates renal failure or other specific diseases.
Aggregation is the ability of platelets to unite among themselves. An increase in this ability and an increase in the norm of aggregation can be observed in diseases such as diabetes mellitus, atherosclerosis, and thrombosis.
APTTV is the most sensitive time indicator for which a blood clot forms. A healthy person takes 30-40 seconds to do this. If the clot forms more quickly, then this may indicate liver disease. A slower education indicates a decrease in blood coagulability and indicates a rare disease.
Blood test for coagulogram
Prothrombin. The normal index is considered to be a concentration of 78-142%.
Fibrinogen. This indicator is different in adults and newborns. In the latter, it should normally be 1.25-3 g / l, and in adults it should be 2-4 g / l.
Antithrombin. The value of this indicator 71-115% is the norm.
Adhesion in the norm( adhesiveness index) is 20-50%.
Aggregation in a healthy person should be 0-20%.
APTTV should normally be 30-40 seconds.